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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17a9780bd76746396e4319704c0d25f6cb0243402abef1ba56d2c8e53de9d103' 
  AND token = 'n06RFVYRd40/Y/UeKR3+K7DQ9iFtjnfV0ykog3Ko/k4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}