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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5efa291eaea09b87fca283b21ba2f6474e8f9c542f49dc0d81cbb42449a873f' 
  AND token = '8r+bs3jSKuKB2BxHD4sUuJnlkrrjiuZ5t0CQMGCLPRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}