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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a2c69b5f17d620733d66ce75f0167dab5e7307816ff9402057e24365c75416d' 
  AND token = 'Bvdk4rBMONLcM7pM9e7UF51ObAzRpVDtTdwpO0A6Aag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}