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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffb052a38cd689a444a384baa39ff9e7af7ffac462fde1029dd8dcec27e26c52' 
  AND token = 'zTVcgl6UsqwTOO59eWrC/+0kSJwwitNAj1+mqKQD+bA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}