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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c35e71d8e7729d937d54da146d4dc69cb8018b407518d7e7cfe443b38512745' 
  AND token = 'V5m6JAQjkDalRb1RQRY4kLIdyWYVFj6yh0SQRese/Aw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}