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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ea46fca1bd2960a489a615e7dafa2ee81ebb76efd3ccad69ab8fecbbca04de3' 
  AND token = 'UI1GfACZwQ8SBggh8rVisbcE6o+f4qO34KFmG+W8cPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}