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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1295ffaf5f088d437eb27b6acb7de7a7c3898e67f5af5f4e04c53a921c5e88a8' 
  AND token = '+SnhgB7lpENAMa2ajhaiERuCrbsHGwe9t6Vt923unVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}