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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20ba636b8c7ab70ff2bb8180e5f741171d757a19db561da2bb5fd0daf5b0f43c' 
  AND token = '1XBOybr/wQLQiPqcm6Za8HCugFd60Y2MIxDkrcdamWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}