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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd208637a34e85209bc78b4a0d6348d550a1720d2559d33d7c29917f5be159b40' 
  AND token = '3bEOPQ17FYfT/abTEQsuI/OZAsr0PbYDunntazp7nOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}