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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4db594bbe250eb03456caec53fde3f65c349fbc3b3256ced907bc04d6d0880f2' 
  AND token = 'EolIyP/N8WCiqpfoesflof5UDgAOsr7kioQXCgjG8Xk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}