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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75f40c274b72a89618ee00edb3f475ab001dfdc9c978451ac7ffe22801b958c2' 
  AND token = 'IKBzX+KSTwrx0fG+KteaNKykij+amFTKkAf3+7u+Dho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}