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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a5d36834d21cc8a68e0ed2a94f8f13cf0cbf7548e8847fa7150cfc0705d2553' 
  AND token = 'xjf/31VyK548m3xnwAcS+7QUOB3O+CUtDJ1DfrKICVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}