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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72b4d56da66e3cc465359e31d831f6d8f3f5ccdb0318526f84843d4a803da0b5' 
  AND token = 'c3rq7PLBjwU0WSrbqk1ugwHvly9ghXR729N5HWuPGuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}