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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d0e80aa44844a19a6bcab575ee148274b0707f4f96c0e88bea2fccc8774a229' 
  AND token = 'Zz+/E1i/pYGDyGusekxrEgAYTdV3XCaI41UBY17CqVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}