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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0c4fc64c2e7d5eeb84c93753283b8feee6aab46439327f87ed4f12c22f9ca28' 
  AND token = 'PTEYya8g7mKULRADRhUu0VRwuC6CnO6EN/By/g/eJ1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}