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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1c3b3d71e6df86303358f3d0a3465f6452880e0e7c38fd0f2f99922cc0c7613' 
  AND token = 'chIHc0as/Chyx2y30SAStPEFlzx4Qi1qZCyc34kRYBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}