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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ce0ff6b268591c62c6771d7d6aeb3f52dd0f9bfab00cb31d8c2c4c323051226' 
  AND token = 'iSL4FT0hDuMcJhUvK3lr/Tnouy9798AtekDoTxQkRRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}