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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec2c21c57d1acc1a2637bf7e29219302f27254830f982200b1f74684bb551137' 
  AND token = '/Xr0zYf0hFHctgFFxKZpdrvg3LlaSSzbTdB29Wn+WbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}