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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6356490355931d2ac777665c88c84c6c34c4f899005cf878654d2d3d18c0cef' 
  AND token = 'W1TTxn9uSf/ncFtbOK/NtwTQx+f6KJGO7Sz9fh9Quas=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}