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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c68d0da0ded1aa1a20789689dfc9fe20f4aa76332f61db16f33e367b22fcc169' 
  AND token = 'DjcVTg2rOK1gbywPNiBsO8LbpAF0aT/TS4I24QhJnnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}