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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c05fefc43163aa4cfb94c2a4fcf0d67cb7497ab230c1da2011a81d9e092e1e8' 
  AND token = 't/+0vVHKDumKFK/AYVRnMNzlCtYUOYET8sSN47pY9DI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}