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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de576c0280ac7ccf99b4ac5b2677171da107e4b3faad6a68d505b92b3b9c5b9d' 
  AND token = 'ZRFETMMGrc9kS/wRkyyo1TNBhGBPkXk38ilNox/D4Lw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}