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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80e4177cf3879b767d8ecee2b0d9b93bf342c982efcca0d7ffd84e18386e9965' 
  AND token = 'W0z9Jv8E8QHIx78wSq4M5u4XlGdOiB4QDCXNkttzmWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}