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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dee291e22b85aed3df740eb6d5e70b6f9184e458a38d279c35469643f1c4cde4' 
  AND token = 'Sfix3GJbz3w0QTf2iHQQcwsY5yX/BKS/OIuQPhfbTeo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}