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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ae2cfe073092286af1572b2dff7f888d3e520ebb76015b8e77085dc3056c336' 
  AND token = 'cXsGURM51rumJhPQ1Io5NE/xgs4Ac/9/ZeQ8LEO9GR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}