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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ce6f28241436eb0a291097b6efe7cb2111304406f2beb5fef526dfd26c8320a' 
  AND token = 'Az1n2rrcWY/tvvBiGpvQVhXVo1RcCErOCLubkid8dn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}