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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '991fb5d85d8cb5c006be51231608c98a8058f5c485cc24403b99241d013072e2' 
  AND token = 'rcEmVn0xo2AmTWQmjZSCh+kW8COlusDGL5PXZphd1z4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}