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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6adc0b5da7296aa88132b61aacb74819f27649a8cbc29c4cbacea3d370c42d06' 
  AND token = 'zs+tVyHlqM2WSwkWflwTrcH5E47FM0puhkPkmGciPLw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}