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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7295eeb3c41bf19837ac818b0a5e70a8d021efa01003178e5d536ca76ecd664b' 
  AND token = 'DwDGK/jwbRNVQ4ZqlQmen+2SfFg0KuhKRrGIUaWaePk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}