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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6728d7c07741aa775a366ab5edfbc45a3524267164b4f2ad6e8b4e0f880e930' 
  AND token = 'NynNEiqyeIMMWdGCJUISpBthxyT1S4FdkIQY43tZngk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}