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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6a24a4efe4051d00ee7356a8e7aa897af24d36b1a09c3f0312ae29cc343bb7f' 
  AND token = 'Zy+ZDZxmWZ9tbA7w2kBV102aQOij07wI5bOBr13Rvlw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}