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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4408c1de07af5994f24f6ca5e754601c4261523ca1a0948a93f23cb460e0723c' 
  AND token = 'A6zQfnZZpVi9USU/tjFN+klrLnwf3MtJAT6tY7ceBbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}