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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a6cf526fad4c48adc6067cf471aadc835aa810abeb8337dd05a24bac134c07d' 
  AND token = 'atMaEK9ztJ6f0AVTppvw2yB9q+tNCOw+puOu5LYqxs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}