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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdb0f492a8bfffd0418f58a550c2773599b5e4a4c9f5dc6fcca2e75756674035' 
  AND token = 'LES3wPVRdR3UskzMF8fLMXQ0CMs9hQE9Zd8tDSFhpgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}