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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7d017d00c46654ba492c49abc7627800d59673b152fc0f686f50aa9b24d10e2' 
  AND token = '8p1gbgtF5yXoJ/EWsEKGmT8z5gd709em87VDD20jWsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}