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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '008502f9f3f4c796bdfd33e30d4312dc6100a2b247a41d9b948a8ecf6de3618f' 
  AND token = 'lL9YbuIR3fzm2WMER4kgxOmXrEA3ccirt3czyOhjZxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}