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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ff78c8fc438685e083e8c501dd62bded15adf1245c09f981577598e63758a0e' 
  AND token = '9LhoT5Z+9pfEV6tkSd1dSWvOhOLL8j9HDnrBaEYsc88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}