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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66a59716b4375732f13c654397c7826f3d0d2dd45eb9dd2ab7b0fb80bbe0c3bd' 
  AND token = 'EFUEF9fvLfXQSpVOS86ImLIcJ++zXqX9iTCzrUNyb0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}