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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bdc1b28d82119b85164a5287d90ed209b4d902977aacc58fe6fdbda66e74d27' 
  AND token = 'Mc5gC/uBq2jS8fMxEJu38UYUxCq+9yItPmU0Vgi2BO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}