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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6ce24da57f090a9f56e5f724ee4d68625240ed188f4fde476de1727af2c5b71' 
  AND token = 'GysEOnqNElJwmUYoAkL6bOk7VkUGQy16SK1tya4cORM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}