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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69f77b0e04048011af5a7ed74df10f0ae61ff2487f772d7dff3afda79e8ff355' 
  AND token = 'dl22XaZp+Vulvc0mYGKiQwP2ofJ8zTMLb3Cp49EsjxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}