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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c60e20e718b7fb9af51b95c9d3d6ffdf5b18aa86f87aea7be7915409cb6a035' 
  AND token = 'K2ZM8JzcWDtTSag5NatxJqaLz0/P8ryQxysmnQzwlhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}