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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2de79a205810536ab48fee69f1598d4333df2c72668860389a21fc0acab43c6' 
  AND token = '4JI4tkCRu8bR3QxEBb2H3joORtxTvkQat5gVSrHJVKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}