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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b5f1056610a50ba5716950ebe66f07d6e49532ff1f42d630ee559ac728d859f' 
  AND token = 'nCw/qpK2HZ0tSSZBFf8SLMofz95RNfi8d8z8gb+yPB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}