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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29e4e43963a1fc36cb21600ecc2b280536632877bd22e784de464996b6f3c29e' 
  AND token = 'LAdSwH5E9la0yv7l+UrTA6fa2oDYRyhnnck3ric/aLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}