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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c0021f3f9a5422fdd877674c01958c52ab69f2200b1ef238eb3b1e02237b953' 
  AND token = '5+ypKuifnh/xi2bL69K6tXpdwv4LDYb9ULGqcNETgDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}