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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd70d81c70896b1b0073ecb8cb27aacfd845aa5bc1c65a3adc3045526907d221c' 
  AND token = 'jyxTFH5BgU+7i1j0ag5WDHwEkVKFkJkQU9YLGq9dItA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}