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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '423e35f2e76ecda403de042041e1662550adfd4e0d467e3cabbf7c8fcfd188a4' 
  AND token = 'Q1rDyABFaUtZCMcauBaFgfsC9+9NKcdHJVEvygRddfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}