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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fa52a17ed50314e485e4cdbf14146518c05f0588acf5cdc960f736ed5905198' 
  AND token = 'd4F10TT8Ch0hPIX0KKAy3Ir64FDaiOIJ/TJyopXAbBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}