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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e44eb9f378aaab3d4a403c6e4217713b90aa4241addb50151751af0f0987260d' 
  AND token = 'qjPRYRFVhRODnOEUrHcdiFSaLIkST4JX6gjvl+owMUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}